I love games that feature the best offense Jason Castro Jersey against one of the best defenses, a hot pa ser against a fierce pa s rush and a great secondary.That's what we get this week in Denver with the playing the on the road. The Falcons have lit it up in four games so far, but the Broncos present a much bigger challenge from the defenses they've faced.Even if can't go at quarterback for the Broncos, which means would start, this is a game about the Falcons offense against the Denver defense.It's against Jr. and .It's against underrated Falcons right tackle . It's against Wade Phillips.I can't wait -- but I think the Broncos will get the better of it.Now here are my Week 5 picks: at The Cardinals will almost certainly be without (concu sion) in this one, so it means it's time. Then again, the 49ers counter with , who is struggling. Cardinals, even without Palmer, will win this one on the road. Pick Zach Duke Jersey : Cardinals 23, 49ers 14 at This is the return of to the lineup. After last week's lo s to the , the Patriots will be focused here. That's bad news for a Browns team with little talent. Brady rolls. Pick: Patriots 33, Browns 14 at The Eagles are coming off a bye, which might not be a good thing considering how they were playing. The Lions are 1-3 and aren't very good right now. Rookie has played well, but something says the Lions will keep this close. Pick: Eagles 27, Lions 26 at This is a game between two teams in bad need of a victory. The Colts have to be one of the bigger disappointments so far. The Bears are playing a tough road game after a division game, and it will show here. The Colts and Andrew Luck get back on track. Pick: Colts 31, Bears 17 at The Titans are playing consecutive road games, and they aren't Miguel Sano Jersey good. That's a bad combination. Miami will get 10 days rest before this one, and that will help. Dolphins playing their second home game of the season will respond and play well. Pick: Dolphins 24, Titans 13 at This is the Beltway Battle. The Redskins have won two straight games to get to 2-2, while the Ravens lost for the first time last week. I think this is the game gets it going and the Ravens slow . Ravens take it. Pick: Ravens 27, Redskins 20 at The Vikings are rolling right now behind their defense. That will present big problems for , who has been inconsistent so far. The Vikings will stay undefeated as plays well again. Pick: Vikings 23, Texans 10 at The Jets didn't look good last week against the , and now face an offensive power in the Steelers. They couldn't contain , so why think they can slow ? is playing bad too. Steelers big. Pick: Steelers 31, Jets 20 Atlanta Falcons at Denver BroncosThis is a tough road test for the Atlanta offense, the highest-scoring unit in the league. Matt Ryan and Julio Jones will be challenged to make plays. The key will be blocking up the Denver front. Trevor Siemian could mi s this game, which would put rookie Paxton Lynch in for his first start. I think even if that's the case, Denver wins. Pick: Broncos 27, Falcons 23 at The Bengals will have had 10 days off before this game. That helps. The Cowboys are 3-1 and isn Anibal Sanchez Jersey 't turning the ball over. But I think this is a game where the Bengals choke off the run and make him beat them. He won't. Bengals take it. Pick: Bengals 23, Cowboys 17 Buffalo Bills at This is a long trip for the Bills after their emotional victory at New England. It's also a second consecutive road game. The Rams are playing great defense, and I think that will show up in this one. Rams take it. Pick: Rams 20, Bills 14 at The Raiders are 3-1 and home for only the second time this season. The first time was when they suffered their only lo s. The Chargers have blown two leads in their two road games. They will again keep it close here, but the Raiders find a way. Pick: Raiders 28, Chargers 27 at This will be back-to-back road games for the Giants off a Monday night game. That's brutal. But it's also against a team coming off a bye. Bad combination. has a big day and won't keep up. Pick: Packers 30, Giants 20 at The Panthers are a shocking 1-3 and have to get things C. J. Cron Jersey turned around. They have an opponent that can make that work. The Panthers have to keep a watch on and his concu sion. But the Bucs aren't playing well. That shows up. Panthers roll.Pick: Panthers 31, Bucs 14