One of those missing courses has to be dex-based, as above, and some have been requesting a return of the juvenile in the OG Diablo. Due to mt nba 2k21 its age, though, and how it's been lost in the shuffle in following courses, a specific"rogue" course would be unlikely. Something related to it remains a possibility, however, as based on fan-demanded courses in Diablo 4, the Assassin is fairly high up there and could fill a nice function.
A melee-oriented course is possible given that Diablo 4 Barbarian is the only one revealed so far, but for one big reason, it's unlikely to be a Crusader, Paladin, or anything of that nature. According to their lore as dedicated heroes inspired by the heavens and the true decimation of Heaven itself, it is unlikely this particular class comes back. Now, some type of variant is not hopeless and a Blackguard at Diablo 4 could be incredibly intriguing however it played, whether it was an anti-hero seeking revenge or as something genuinely evil (not seen in Diablo actually ).
It may seem like a perplexing request, but lore-wise, it might be intriguing to play with an Angel fighting hordes of demons. The decimation of Heaven may even lend itself this way, but it's not likely to take place at launch, in DLC, or ever really for 2 main reasons.
To begin with, the idea of this franchise is mortals beating allies, and also an Angel is clearly not a mortal. The latter may provide in at some point, as seen between the first two games, and it's a big narrative point. Secondly, Diablo has never been a match about needing a committed Healer class and to Buy NBA 2K21 Mt do so would include a strange gameplay component to Diablo 4 that is quite unnecessary.